Friday, May 21, 2010

Personalised Medicine: Check your DNA at the door

Personalized Medicine: Check your DNA at the door - SmartPlanet

College kids survive on a diet of beer and pizza, but personalized medicine might soon change that. This summer, UC - Berkeley wants 5,500 new students to participate in a DNA experiment: The students will be required to return a swab of their cheek cells, so they can find out if they have the genes to metabolize folate, lactose, and alcohol.

Ideally, the students who lack the genes will modify their behavior accordingly. They would eat more green vegetables, avoid milk products (and prepare to explain to everyone and their mother why they now drink soy milk), and hold back on the drinking. This seems like a wonderful idea, but freshmen at a party might not really care if they don’t have the genes to metabolize alcohol.

I definitely would have benefited from this test, as I found out after college I could not digest milk and only had one of the genes to metabolize alcohol (which I totally blame on my Asian heritage).

The Berkeley experiment seems pretty innocent:
The idea is not to identify potentially dangerous genes in students’ samples, but to point out traits that can be managed through behavior, said Jasper Rine, a professor of genetics, genomics and development. “We want to get people to appreciate that there are things you can do that enhance your health based on the genes you have,” he said. “There are concrete, actionable, specific steps that do enhance quality of life. This is the message of the post-genomic era.” [USA Today]

The results will remain anonymous - the students can check their genes by entering a barcode given to them. There’s been some push back as people worry that the university is forcing people to test the “unproven technology”.

When the consumer testing companies claim to interpret people’s risk of developing common diseases, critics worry about the misuse of information. When Walgreens announced that it would sell Pathway Genomics at its drug stores, it attracted the FDA’s attention (in a bad way). I couldn’t really see someone coming in to buy a soda and chips pick up a genetic test on a whim anyway.

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